Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
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منابع مشابه
Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
Production of chemicals and biofuels through microbial fermentation is an economical and sustainable alternative for traditional chemical synthesis. Here we present the construction of a Saccharomyces cerevisiae platform strain for high-level production of very-long-chain fatty acid (VLCFA)-derived chemicals. Through rewiring the native fatty acid elongation system and implementing a heterologo...
متن کاملMetabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals.
As the serious effects of global climate change become apparent and access to fossil fuels becomes more limited, metabolic engineers and synthetic biologists are looking towards greener sources for transportation fuels. In recent years, microbial production of high-energy fuels by economically efficient bioprocesses has emerged as an attractive alternative to the traditional production of trans...
متن کاملFatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
Volatile energy costs and environmental concerns have spurred interest in the development of alternative, renewable, sustainable, and cost-effective energy resources. Environment-friendly processes involving microbes can be used to synthesize advanced biofuels. These fuels have the potential to replace fossil fuels in supporting high-power demanding machinery such as aircrafts and trucks. From ...
متن کاملThe use of metabolic engineering to produce fatty acid-derived biofuel and chemicals in Saccharomyces cerevisiae: a review
Production of fatty acid-derived biofuels and chemicals have garnered attention in recent years owing to their potential to replace petroleum and plant oil-derived products. Through the metabolic engineering of the fatty acid metabolism pathway, advanced fuels and chemicals such as free fatty acid, triacylglycerol, biodiesel, fatty alcohols, alkanes/alkene, R-3-hydroxybutyric acid, polyhydroxya...
متن کاملMetabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel
BACKGROUND Biodiesel is a mixture of fatty acid short-chain alkyl esters of different fatty acid carbon chain lengths. However, while fatty acid methyl or ethyl esters are useful biodiesel produced commercially, fatty acid esters with branched-chain alcohol moieties have superior fuel properties. Crucially, this includes improved cold flow characteristics, as one of the major problems associate...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2017
ISSN: 2041-1723
DOI: 10.1038/ncomms15587